Synthesis of New Potential NMDA Antagonist Based on Acylphosphonate Derivatives
Artículo
Autoría:
SALOMON, CLAUDIO JAVIERFecha:
1999Editorial y Lugar de Edición:
TAYLOR & FRANCIS LTDRevista:
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, vol. 147 (pp. 367-367) TAYLOR & FRANCIS LTDResumen *
In recent years intensive pharmacological research is focused on the N-methyl-D-aspartate (NMDA) receptor, which has been implicated in normal neuronal hnctioning, including excitatory synaptic transmission, as well as in the pathologies of the central nervous system such epilepsy, Alzheimer and Parkinson´s disease, and neurodegeneration following a stroke. Información suministrada por el agente en SIGEVAPalabras Clave
NMDA ANTAGONISTSSYNTHESISACYLPHOSPHONATES