Science and Technology Production
Synthesis of New Potential NMDA Antagonist Based on Acylphosphonate Derivatives
Article
Authorship:
SALOMON, CLAUDIO JAVIERDate:
1999Publishing House and Editing Place:
TAYLOR & FRANCIS LTDMagazine:
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, vol. 147 (pp. 367-367) TAYLOR & FRANCIS LTDSummary *
In recent years intensive pharmacological research is focused on the N-methyl-D-aspartate (NMDA) receptor, which has been implicated in normal neuronal hnctioning, including excitatory synaptic transmission, as well as in the pathologies of the central nervous system such epilepsy, Alzheimer and Parkinson´s disease, and neurodegeneration following a stroke. Information provided by the agent in SIGEVAKey Words
NMDA ANTAGONISTSSYNTHESISACYLPHOSPHONATES