Science and Technology Production
Synthesis of New Potential NMDA Antagonist Based on Acylphosphonate Derivatives

Article

Date
1999
Publishing House and Editing Place
TAYLOR & FRANCIS LTD
Magazine
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, vol. 147 (pp. 367-367) TAYLOR & FRANCIS LTD
Summary Information provided by the agent in SIGEVA
In recent years intensive pharmacological research is focused on the N-methyl-D-aspartate (NMDA) receptor, which has been implicated in normal neuronal hnctioning, including excitatory synaptic transmission, as well as in the pathologies of the central nervous system such epilepsy, Alzheimer and Parkinson´s disease, and neurodegeneration following a stroke.
Key Words
NMDA ANTAGONISTSSYNTHESISACYLPHOSPHONATES