Producción CyT
Biocatalysis applied to the synthesis of valuable triazole-containing derivatives

Capítulo de Libro

Autoría
Aníbal Cuetos ; BISOGNO, FABRICIO ROMAN ; Iván Lavandera
Fecha
2013
Editorial y Lugar de Edición
ROYAL SOC CHEMISTRY
Libro
Targets in Heterocyclic Systems, Chemistry and Properties (pp. 177-215)
ROYAL SOC CHEMISTRY
ISBN
978-8886208703
Resumen Información suministrada por el agente en SIGEVA
The use of enzymes applied to organic synthesis is gaining more and more relevance due to the mild reaction conditions needed and high selectivities that these catalysts offer. Herein examples about the biocatalyzed synthesis of (chiral) 1,2,3-, 1,2,4-, and benzotriazole-based compounds will be described. While in some cases the enzymatic transformation directly modified these derivatives, in other cases it occurred over a suitable precursor of an interesting triazole-derived target. Finally, s... The use of enzymes applied to organic synthesis is gaining more and more relevance due to the mild reaction conditions needed and high selectivities that these catalysts offer. Herein examples about the biocatalyzed synthesis of (chiral) 1,2,3-, 1,2,4-, and benzotriazole-based compounds will be described. While in some cases the enzymatic transformation directly modified these derivatives, in other cases it occurred over a suitable precursor of an interesting triazole-derived target. Finally, some examples about the rational use of one-pot tandem or cascade protocols to synthesize these heterocycles will also be underlined.
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Palabras Clave
enzymesbiocatalysistriazoleantifungal