Science and Technology Production
Book Chapter
Authorship
Aníbal Cuetos
;
BISOGNO, FABRICIO ROMAN
;
Iván Lavandera
Date
2013
Publishing House and Editing Place
ROYAL SOC CHEMISTRY
Book
Targets in Heterocyclic Systems, Chemistry and Properties
(pp. 177-215)
ROYAL SOC CHEMISTRY
ROYAL SOC CHEMISTRY
ISBN
978-8886208703
Summary
Information provided by the agent in
SIGEVA
The use of enzymes applied to organic synthesis is gaining more and more relevance due to the mild reaction conditions needed and high selectivities that these catalysts offer. Herein examples about the biocatalyzed synthesis of (chiral) 1,2,3-, 1,2,4-, and benzotriazole-based compounds will be described. While in some cases the enzymatic transformation directly modified these derivatives, in other cases it occurred over a suitable precursor of an interesting triazole-derived target. Finally, s...
The use of enzymes applied to organic synthesis is gaining more and more relevance due to the mild reaction conditions needed and high selectivities that these catalysts offer. Herein examples about the biocatalyzed synthesis of (chiral) 1,2,3-, 1,2,4-, and benzotriazole-based compounds will be described. While in some cases the enzymatic transformation directly modified these derivatives, in other cases it occurred over a suitable precursor of an interesting triazole-derived target. Finally, some examples about the rational use of one-pot tandem or cascade protocols to synthesize these heterocycles will also be underlined.
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Key Words
enzymesbiocatalysistriazoleantifungal