Producción CyT
Penfigoide ocular cicatrizal: Manifestaciones clínicas, diagnóstico y manejo actual

Artículo

Autoría
Schlaen, Bernardo Ariel ; Montoya, Juliana ; Heredia, Milagros ; Ficoseco, Carla ; DOMINGUEZ, LUCIA
Fecha
2022
Editorial y Lugar de Edición
Arhketypo
Revista
AUTOINMUNIDAD, vol. 5 (pp. 114-120) - ISSN 2545-6032
Arhketypo
ISSN
2545-6032
Resumen Información suministrada por el agente en SIGEVA
Ocular cicatricial pemphigoid is a progressive, bilateral, chronic disease, of autoimmune etiology, in which autoantibody deposits are observed in mucosal basement membranes. It is regarded as a mucous membrane pemphigoid subtype, a bullous dermatitis, characterized by blistering in mucosal tissues of nose, mouth, respiratory tract, and genitalia. As a counterpart, ocular involvement without systemic manifestations is observed up to one third of the patients. Ophthalmological presentation is as... Ocular cicatricial pemphigoid is a progressive, bilateral, chronic disease, of autoimmune etiology, in which autoantibody deposits are observed in mucosal basement membranes. It is regarded as a mucous membrane pemphigoid subtype, a bullous dermatitis, characterized by blistering in mucosal tissues of nose, mouth, respiratory tract, and genitalia. As a counterpart, ocular involvement without systemic manifestations is observed up to one third of the patients. Ophthalmological presentation is asymmetric, with a conjunctival inflammation which evolves to fibrosis, leading to an ocular surface insufficiency, and infectious and inflammatory complications, as well as a potentially devastating visual loss. A timely diagnosis, with an interdisciplinary approach and a suitable systemic treatment, are pivotal and they require a high level of experience, since this condition may be extremely difficult in identifying and treating.
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Palabras Clave
CONJUNTIVITISPENFIGOIDEINMUNOSUPRESORTRATAMIENTO
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