Producción CyT
One-pot synthesis and insecticidal activity of 5-amino-1- aryl-1H-pyrazole-4-carbonitriles

Artículo

Autoría
Plem Silvana Cristina ; MACHUCA, LAURA MARCELA ; Gutiérrez Carolina Guadalupe ; Coll Aráoz Maria Victoria ; Van Nieuwenhove Guido Alejandro ; Virla Eduardo Gabriel ; Murguía Marcelo César
Fecha
2020
Editorial y Lugar de Edición
DR JYOTI GARG
Revista
RESEARCH JOURNAL OF CHEMISTRY AND ENVIRONMENT, vol. 24 (pp. 102-108) DR JYOTI GARG
Resumen Información suministrada por el agente en SIGEVA
Synthesis of 5-amino-1-aryl-1H-pyrazole-4-carbonitriles was performed by direct condensation of(ethoxymethylene)malononitrile and aryl hydrazines.The resulting N,N-containing heterocycles possess insecticidal properties relative to microlepidoptera species, plant phatogens. The insecticidal activity of four novel synthetic N-aryl pyrazoles to Tuta absoluta larvae was assessed. Fipronil, a well-known aryl pyrazole insecticide, was also tested as the positive control. A generalized linear model r... Synthesis of 5-amino-1-aryl-1H-pyrazole-4-carbonitriles was performed by direct condensation of(ethoxymethylene)malononitrile and aryl hydrazines.The resulting N,N-containing heterocycles possess insecticidal properties relative to microlepidoptera species, plant phatogens. The insecticidal activity of four novel synthetic N-aryl pyrazoles to Tuta absoluta larvae was assessed. Fipronil, a well-known aryl pyrazole insecticide, was also tested as the positive control. A generalized linear model reported significant differences in efficacy and tomato leaf consumption among the different treatments. Fipronil treatment was the most effective one (100% mortality after 48 h), followed by 5-amino-1-phenyl-1H-pyrazole-4-carbonitrile treatment (3c) (75% mortality after 48 h) and 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)-phenyl-1H-pyrazole-4-carbonitrile treatment (3b) (60% mortality after 48 h). These compounds, with simpler structures than Fipronil could be used as novel insecticides.
Ver más Ver menos
Palabras Clave
CHEMICAL PEST CONTROLN-ARYL PYRAZOLESSOLANUM LYCOPERSICUM LLEPIDOPTERATUTA ABSOLUTA