Comparative study of biological activity of fluorinated 5- aminopyrazoles on Spodoptera frugiperda

Artículo

Autoría

PLEM, SILVANA CRISTINA ; Carrió, María Josefina ; Vaira, Stella Maris ; Müller, Diana María ; MURGUIA, MARCELO CESAR

Fecha

2016

Editorial y Lugar de Edición

AD Publications

Revista

International Journal of Environmental & Agriculture Research, vol. 2 (pp. 88-93) - ISSN 2454-1850
AD Publications

ISSN

2454-1850

Resumen Información suministrada por el agente en SIGEVA

Several derivatives aminopyrazoles, which are a new class of synthetic insecticide agents, have shown biological activity against lepidopteran, such as Spodoptera frugiperda. The aim of this work was to assess the biological activity of these synthesized compounds. For this purpose, derivatives of 5-amino-1-aryl-1H-pyrazole-4-carbonitriles were synthesized from commercially available aryl hydrazines and (ethoxymethylene)malononitrile. Three compounds (A, B, C) were tested for in vitro biologica... Several derivatives aminopyrazoles, which are a new class of synthetic insecticide agents, have shown biological activity against lepidopteran, such as Spodoptera frugiperda. The aim of this work was to assess the biological activity of these synthesized compounds. For this purpose, derivatives of 5-amino-1-aryl-1H-pyrazole-4-carbonitriles were synthesized from commercially available aryl hydrazines and (ethoxymethylene)malononitrile. Three compounds (A, B, C) were tested for in vitro biological activity; two of them, A [5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-1H-pyrazole-4-carbonitrile] and B [5-amino-1-(perfluorophenyl)-1H-pyrazole-4-carbonitrile] showed promising activity, particularly the compound A.

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Palabras Clave

Spodoptera frugiperdaaminopyrazolebiological activitypolyphagous lepidopteran.

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http://hdl.handle.net/11336/23815