Producción CyT
Congreso
Autoría
KRMPOTIC, CECILIA MARIANA
;
Nishida Fabian
;
Galliari F. C.
;
Strobl-Mazzulla P
;
Barbeito C. G.
Fecha
2016
Editorial y Lugar de Edición
Instituto de Histología y Embriología ?Dr. Mario H. Burgos? (IHEM-CONICET), Facultad de Ciencias Médicas, U.N.Cuyo. Casilla de Correo 56, (5500) Mendoza, Argentina,
ISSN
1667-5746
Resumen
Información suministrada por el agente en
SIGEVA
Neural crest cells give rise to various cell populations in the adult vertebrate including facial bones. In some reptiles, such as turtles and crocodiles, neural crest is involved in the origin of the osteoderms (dermis ossifications). In modern mammals,osteoderms are only present in the Dasypodidae (armadillos, tatus, etc) skin. The osteoderm formation is a complex process including both metaplastic and intra-membranosous ossification mechanisms. At present there are not studies about a possib...
Neural crest cells give rise to various cell populations in the adult vertebrate including facial bones. In some reptiles, such as turtles and crocodiles, neural crest is involved in the origin of the osteoderms (dermis ossifications). In modern mammals,osteoderms are only present in the Dasypodidae (armadillos, tatus, etc) skin. The osteoderm formation is a complex process including both metaplastic and intra-membranosous ossification mechanisms. At present there are not studies about a possible neural crest origin of the of the Dasypodidae osteordems. In this work we focus on Dasypus hybridus,a Dasypodidae species, toassess the presence of a neural crest marker (the HNK-1 epitope), which has been previously found in the osteoderm precursor tissue of reptiles. Samples of dorsal and ventral skin of fetus and neonates of D. hybridus were processed forimmunohistochemistry using a HNK-1 antiobody. The ventral skin mesenchymal or connective tissues were negative, but in the dorsal region of a fetus (total length 90.8 mm) positive cells were found in the subepidermal region of the undifferentiated dermis. Positive cells were absent in the region between the epidermal scales, where the osteoderms never develops. These results are the first evidence of a potential neural crest origin of poscranial ossifications in mammals. Further works are in progress, using others neural crest markers and alternative designs to demonstrate negative melanocyte lineages in these cells.
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Palabras Clave
Dasypus hybridusHNK-1osteodermneural crest