Stereoselective synthesis of chiral precursors of cyclobutane carboxyclic nucleosides and oligopeptides

Artículo

Resumen *

Versatile and highly efficient synthetic routes leading to optically active cyclobutanones,
-amino acids and -amino alcohols are described. These compounds are relevant synthetic precursors to enantiopure cyclobutane carbocyclic nucleosides and oligopeptides. (−)-(S)-Verbenone is the chiral starting material used and the key synthetic steps involve concerted rearrangements in acidic medium. Información suministrada por el agente en SIGEVA