Producción CyT
Congreso
Autoría
Anzardi Ruffino, L.
;
Yáñez Santos, A.M
;
Suárez, J.
;
MARY, VERONICA SOFIA
;
Theumer, M.
;
Lascano, H.R.
;
Lescano López, I.
Fecha
2025
Editorial y Lugar de Edición
Sociedad Argentina de Fisiología Vegetal
Resumen
Información suministrada por el agente en
SIGEVA
Autophagy is a highly conserved process in eukaryotes and serves as amajor quality control system for the degradation of damaged or unnecessarycellular components to maintain homeostasis. While bulk autophagy is activatedunder nutrient deprivation, selective autophagy is primarily responsible forthe targeted degradation of specific components via receptors such as NBR1 (Neighbourof Breast cancer 1). In plants, both forms of autophagy are essential inimmunity, contributing to the balance between...
Autophagy is a highly conserved process in eukaryotes and serves as amajor quality control system for the degradation of damaged or unnecessarycellular components to maintain homeostasis. While bulk autophagy is activatedunder nutrient deprivation, selective autophagy is primarily responsible forthe targeted degradation of specific components via receptors such as NBR1 (Neighbourof Breast cancer 1). In plants, both forms of autophagy are essential inimmunity, contributing to the balance between cell survival and death.Temperature increases modify developmental programs and plant-pathogeninteractions. In Arabidopsis thaliana, thermomorphogenesis (29 °C)promotes growth but alters hormone signaling, increasing susceptibility topathogens. We previously reported that thermomorphogenesis combined withinfection by virulent Pseudomonas syringae enhances autophagic flux andNBR1 turnover. In this study, we examined the role of selective autophagymediated by NBR1 in hormonal and defense responses under thermomorphogenesis.Wild-type (WT) and nbr1-2 mutant plants infected with P. syringaepv. maculicola were grown at 22 °C or 29 °C. Bacterial growth, hormonelevels, and the expression of hormone-related genes were analyzed. Resultsshowed increased susceptibility and altered gene expression in nbr1-2mutants at 29 °C. Notably, ABA synthesis and signaling were enhanced in nbr1-2compared to WT. The physical interaction between NBR1 and ABI5, along withelevated ABI5 protein levels in nbr1-2, suggests that NBR1 may targetABI5 for selective degradation. These findings support a role for NBR1 inmodulating hormonal signaling and enhancing plant defense under elevatedtemperatures via selective autophagy.
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Palabras Clave
THERMOMORPHOGENESISARABIDOPSIS THALIANANBR1SELECTIVE AUTOPHAGYHORMONE SIGNALING