Producción CyT
Sustainable development of AB-type carbonate apatite from animal bone: Sintering, characterization, and biomedical potential
Artículo
Autoría:
Guerra-López, José R. ; Bianchi, Ana E. ; Ramos, Marcelo A. ; Ubertino, Mauro ; Ferraresi-Curotto, Verónica ; Güida, Jorge A. ; Rau, Julietta V. ; Echeverría, Gustavo A.Fecha:
2025Editorial y Lugar de Edición:
ELSEVIER SCI LTDRevista:
CERAMICS INTERNATIONAL ELSEVIER SCI LTDResumen *
Cortical and cancellous bone samples of different origins (bovine and porcine) subjected to two different sintering processes at 600 and 800 ◦C, have been studied by thermogravimetric analysis, Fourier transform infrared spectroscopy, X-ray diffraction, and scanning electron microscopy. Special emphasis was placed on obtaining cancellous bone blocks because their inherent porosity facilitates osseointegration processes, favoring integration with the bone tissues to be repaired. To achieve this, bovine and porcine bones were subjected to three different methods to ensure complete deproteinization. The key difference between the methods lies in the use of chemicalreagents, aimed at removing the organic components while preserving the thermally stable crystalline phase. The results reveal that the thermal stability of the carbonate apatite phase remained intact up to 800 ◦C, and that all of the sintered samples retain the carbonate apatite phase with different percentages of carbonate. This study suggests that the bovine bone sintered at 600 ◦C holds promise as a biomaterial useful in bone repair applications.For this conclusion, it has been taken account that various microstructural features, like mean pore size, total pore volume, and the size and amount of interconnections, significantly influence the rate and quality of bone integration. Our observations demonstrate that the conversion of natural cancellous bone derived from animals can yield a natural, porous carbonate apatite (CHap) structure with potential for biomedical use. Información suministrada por el agente en SIGEVAPalabras Clave
Carbonate apatite Rietveld analysis Infrared spectroscopyX-ray powder diffraction Cancellous bone Thermal treatment