Producción CyT
Magnetite: a Green, Sustainable and Recyclable Catalyst for Direct Synthesis of Thioesters by C−H Activation
Artículo
Fecha:
2025Editorial y Lugar de Edición:
WILEY-V C H VERLAG GMBHRevista:
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY WILEY-V C H VERLAG GMBHResumen *
A green and sustainable approach to the direct synthesis of thioesters has been developed using Fe3O4 as a low-cost, easily prepared, reusable and environmentally safe catalyst. The cross dehydrogenative coupling (CDC) of various thiols and aldehydes in water, or even in the absence of solvent, using tertbutylhydroperoxide as oxidant, under ligand and base-free mild conditions, afforded the corresponding thioesters in good to excellent yields. This simple protocol features broad substrate scope, good compatibility with different functional groups, as well as high atom-efficiency. The scalability, ease of (magnetic) recovery and reuse of the magnetite catalyst are additional ecofriendly attributes of this methodology. Moreover, the broad synthetic applications of thioesters further highlight the potential utility of the present protocol. Información suministrada por el agente en SIGEVAPalabras Clave
C-H ACTIVATIONTHIOESTERSCATALYSISMETAL OXIDES