Producción CyT
Ferroptosis in plants: triggers, proposed mechanisms and the role of iron in modulating cell death

Artículo

Autoría
DISTEFANO, AYELEN MARIANA ; Lopez, Gabriel Alejandro ; Setzes, Nicolás ; Marchetti, Maria Fernanda ; Cainzos Gelabert, Maximiliano Guillermo ; Cascallares, María Milagros ; ZABALETA, EDUARDO JULIAN ; PAGNUSSAT, GABRIELA CAROLINA
Fecha
2020
Editorial y Lugar de Edición
OXFORD UNIV PRESS
Revista
JOURNAL OF EXPERIMENTAL BOTANY, vol. 72 (pp. 2125-2135) OXFORD UNIV PRESS
Resumen Información suministrada por el agente en SIGEVA
Regulated cell death plays key roles during essential processes along the plant life cycle. It takes part of specific developmental programs and maintains the organism homeostasis in response to unfavorable environments. Ferroptosis is a recently discovered iron-dependent cell death pathway characterized by the accumulation of lipid reactive oxygen species. Ferroptosis in plants shares all the main hallmarks described for ferroptosis in other systems. Those specific features include biochemical... Regulated cell death plays key roles during essential processes along the plant life cycle. It takes part of specific developmental programs and maintains the organism homeostasis in response to unfavorable environments. Ferroptosis is a recently discovered iron-dependent cell death pathway characterized by the accumulation of lipid reactive oxygen species. Ferroptosis in plants shares all the main hallmarks described for ferroptosis in other systems. Those specific features include biochemical and morphological signatures that seem conserved among species. However, plant cells have specific metabolic pathways and a high degree of metabolic compartmentalization. Together with their particular morphology, these features add more complexity to the plant ferroptosis pathway. In this review, we summarize the most recent advances in elucidating the roles of ferroptosis in plants, focusing on specific triggers, main players and underlying pathways.
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Palabras Clave
IRON METABOLISMARABIDOPSISCELL DEATHFERROPTOSIS
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