Producción CyT
Congreso
Autoría
Carello, María Agostina
;
Corvalán, Nicolás
;
Keller, Greta
;
Martínez, Carlos
;
Calandri, Ismael Luis
;
Allegri, Ricardo Francisco
;
CRIVELLI, LUCÍA
Fecha
2023
Editorial y Lugar de Edición
Alzheimer's Association
Resumen
Información suministrada por el agente en
SIGEVA
Introduction and Objective. Craft Story 21 is a practical, comprehensive, and freely available tool toassess episodic memory in patients with memory impairment. Though it is part of the UDS3neuropsychological battery and has been translated into Spanish, it still does not have normativevalues in Spanish that adjust to our specific population. Furthermore, the original test does not havea recognition phase to increase the specificity of the memory profile by allowing a distinctionbetween differe...
Introduction and Objective. Craft Story 21 is a practical, comprehensive, and freely available tool toassess episodic memory in patients with memory impairment. Though it is part of the UDS3neuropsychological battery and has been translated into Spanish, it still does not have normativevalues in Spanish that adjust to our specific population. Furthermore, the original test does not havea recognition phase to increase the specificity of the memory profile by allowing a distinctionbetween different amnesic profiles. Therefore, this study has two main aims: 1) the generation ofnormative data for the Craft Story 21 memory test, adjusting to the characteristics of our Spanish-speaking country according to sex, age, and educational level; and 2) the design and validation ofthe recognition phase of the test and the assessment of its psychometric properties.Materials and Methods. The baremization sample was composed of 81 healthy participants aged 41to 91, assessed through the Uniform Data Set III (UDS III) battery of the National Alzheimer'sCoordinating Center (NACC). The design of the recognition phase included three steps: (1)construction of the scale and review by experts, (2) pilot study, and (3) analysis of its psychometricproperties. In the latter, 190 participants were recruited and classified into two groups matched byage, sex, and educational level: Mild Cognitive Impairment (MCI n=96) according to Petersen's(1999) criteria and healthy controls (HC n=94). In addition, the diagnostic accuracy of the test wasstudied by the ROC curve method, its concurrent validity by correlation with other memory tests(RAVLT), and its internal consistency with Cronbach's alpha test.Results. For the baremization aim, a sample was divided into 4 age groups (41-51, 51-61, 61-71,and >72 years), two educational levels (6-12 years and >12 years), and by sex (male and female).Performance was significantly different between age groups (p < 0.003**). No significantdifferences were found in Craft Story 21 performance between education (p > 0.09) or sex (p >0.56) groups within each age group. Normative values in terms of means and standard deviationsare presented for each group. Regarding the design of the recognition phase, the groups did notshow significant differences in age (p= 0.13), sex (p= 0.88), or education (p= 0.33). The overallscore of the Craft Story 21 test showed the ability to discriminate between healthy controls frompatients with MCI (sensitivity = 81.6% and specificity = 72.4%). Its diagnostic accuracy by phase(immediate AUC= 0.86; delayed AUC= 0.86 and recognition AUC= 0.75) was superior to ReyAuditory and Verbal Learning Test (RAVLT): immediate (AUC= 0.79), delayed (AUC= 0.82) andrecognition (AUC= 0.74). It presented evidence of concurrent validity with RAVLT in itsimmediate (r=0.56, p<0.001), delayed (r= 0.66, p<0.001), and recognition (r= 0.37, p<0.001) trials.The instrument also presented evidence of reliability (α= 0.82).Conclusions. The Craft Story 21 test is a practical, brief and multicultural test. Thus, havingappropriate scales for the specific population to be assessed to a more accurate and precisedescription of the memory profile. Additionally, the new Recognition phase of the test showedevidence of validity and reliability for assessing memory processes.
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Palabras Clave
Craft Story.Standardization.ScalesMemory