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IASP 2022 World Congress on Pain - RADIOFREQUENCY-EVOKED POTENTIALS: A NEW METHOD FOR THE ASSESSMENT OF THE NOCICEPTIVE SYSTEM
Congreso
Fecha:
2023Editorial y Lugar de Edición:
IASPResumen *
Generating nociceptive-specific stimulus to evoke synchronized brain responses (i.e., evoked potentials, EP) is challenging [1]. Laser stimulation is the gold standard to selectively activate Aδ and/or C fibers [2], but the equipment isexpensive, and requires special safety measures. Radiofrequency (RF) stimulation, in the range of 200 kHz to 3.3 Mhz, generates effects exclusively due to tissue heating, so that in strictly physiological termsthe responses to these stimuli would be similar to those generated by lasers.The aim of this study was to validate radiofrequency stimulation as an alternative for selective nociceptive activation, by recording and analyzing radiofrequency-evoked potentials (RFEP) Seventeen volunteers (5 females) participated in a single experimental session, in which they were stimulated on the dorsum of the hand and foot.RF stimulation was delivered by a custom-madedevice, producing RF currents at 400 kHz (Fig. 1).Stimulus consisted of a single 25-ms pulsedelivered through a standard electrocautery probe.For comparison purposes, standard electrical stimuli(ES) were delivered through a BIOPAC STMISOLAstimulator. Stimulus configuration was similar(single 25-ms pulse) delivered through a concentric16-pin electrode.Stimulation intensities were set in both cases as amultiplier of the detection threshold, that clearlyelicited a pricking sensation, and was similarbetween stimulation types.We developed a new method for the assessment ofthe nociceptive system based on RF stimulation andEP recording.RF elicits longer latencies in the EP peaks comparedwith ES stimulation. This difference can beassociated with selective activation of nociceptive Aδfibers. Información suministrada por el agente en SIGEVAPalabras Clave
SMALL FIBERSNOCICEPTIONEEGRADIOFREQUENCY