CONICET Community
Internal doctoral strategic topics
Speciality
Obtención y caracterización de gelatina de pescado
Scientific discipline
Food engineering and Biotechnology
Topic
CHARACTERIZATION AND TECHNOLOGICAL PROSPECTIVE OF GELATIN OBTAINED FROM WASTE FROM FISH PROCESSING
Workplace
GRUPO DE INV. PRESERVACION Y CALIDAD DE ALIMENTOS
(GIPCAL, CIC)
Dependencies
- COMISION DE INVESTIGACIONES CIENTIFICAS DE LA PROVINCIA DE BUENOS AIRES
- INSTITUTO EN CIENCIA Y TECNOLOGIA DE ALIMENTOS Y AMBIENTE
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| Address: |
| AV.JUAN B.JUSTO 4302, 7600 - Mar del Plata - Buenos Aires - Argentina |
Summary
Information provided by the agent in
SIGEVA
Drosophila melanogaster hemolymph cells are confirmed as a model to study the activation of immune system due to foreign stimuli like iron nanoparticles. The toxicity of nanoparticles is a cause for concern due to their effect on human health and the environment. The aim of this study was to detect the activation of cellular immune response in Drosophila larvae through the observation of hemolymph composition, DNA damage and larval viability, after the exposure to 500 ppm and 1000 ppm chitosan-...
Drosophila melanogaster hemolymph cells are confirmed as a model to study the activation of immune system due to foreign stimuli like iron nanoparticles. The toxicity of nanoparticles is a cause for concern due to their effect on human health and the environment. The aim of this study was to detect the activation of cellular immune response in Drosophila larvae through the observation of hemolymph composition, DNA damage and larval viability, after the exposure to 500 ppm and 1000 ppm chitosan-coated magnetite nanoparticles for 24 hours. Our results showed activation of cellular immune response after exposure to the nanoparticles owing to the increment of hemocytes, the emergence of lamellocytes and the presence of apoptotic hemocytes. In addition, chitosan-coated magnetite nanoparticles produce DNA damage detected by comet assay as well as low viability of larvae. No DNA damage is showed at 500 ppm. The cellular toxicity is directly associated with 1000 ppm.
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Lines of Investigation
Genotoxicidad
Natural and exact sciences
- Biological sciences
- Biodiversity conservation
Technological Capacities
6 - Biological sciences
6.2 - Biology/Biotechnology
- 6.2.1 - Biochemistry/Biophysics
- 6.2.2 - Cellular and Molecular Biology
- 6.2.3 - Genetic Engineering
- 6.2.4 - In vitro Testing, Trials
- 6.2.5 - Microbiology
- 6.2.6 - Molecular design
- 6.2.7 - Toxicology
- 6.2.8 - Bionics
- 6.2.9 - Enzyme Technology
- 6.2.10 - Synthetic Biology
- 6.2.11 - Protein Engineering
6.3 - Genome Research
- 6.3.1 - Bioinformatics
- 6.3.2 - Gene Expression, Proteom Research
- 6.3.3 - Population genetics
6.4 - Micro- and Nanotechnology related to Biological sciences
6.6 - Industrial Biotechnology
- 6.6.1 - Bio- Composites
- 6.6.2 - Biobased chemical building blocks
- 6.6.3 - Biobased high-performance materials
- 6.6.4 - Biobased Materials
- 6.6.5 - Biological Nanomaterials
- 6.6.6 - Biolubricants
- 6.6.7 - Bioplastics
- 6.6.8 - Biopolymers
- 6.6.9 - Bioprocesses
Key Words
Hemolymphapoptosischitosan magnetite nanoparticles
Education
2022 - 2023
Máster en Ciencias Ambientales Evaluación del Impacto Ambiental
UNIVERSIDAD YACAMBÚ
2021 - 2022
Máster en Bioética
UNIVERSITAT INTERNACIONAL VALENCIANA
2020 - 2021
Especialista en Gestión de Proyectos de Desarrollo
AREA DE ESTADO Y POLITICAS PUBLICAS, FACULTAD LATINOAMERICANA DE CIENCIAS SOCIALES
2009 - 2016
Ingeniero en Biotecnología
DEPARTAMENTO DE CIENCIAS DE LA VIDA Y LA AGRICULTURA, UNIVERSIDAD DE LAS FUERZAS ARMADAS
Directed by:
CZERNER, MARINA
Scientific Research Career at CONICET
CZERNER, Marina
Scientific Research Career at CONICET
Co-directed by:
AGUSTINELLI, SILVINA PAOLA
Scientific Research Career at CONICET
AGUSTINELLI, Silvina Paola
Scientific Research Career at CONICET
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