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CARVELLI, FLAVIA LORENA

INVESTIGADOR ADJUNTO

SPECIALITY:

Biología Celular - Transporte Intracelular - Biología de la Reproducción

Scientific discipline:

Bioquímica y Biología Molecular - Biología

Topic:

Estudio del sistema endosomal-lisosomal en diferentes modelos biológicos . The endosomal-lysosomal system in different biological models.

Workplace

INSTITUTO DE HISTOLOGIA Y EMBRIOLOGIA DE MENDOZA DR. MARIO H. BURGOS (IHEM, CONICET-UNCU) Depends on
Address:
EDIFICIO IHEM CENTRO UNIVERSITARIO S/N, M5502JMA - Mendoza - Argentina

Contact:

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S&T Expertise*

I studied mutations of the BRCA1 and BRCA2 genes of healthy women with a familiar history of breast cancer. I received training on mismatched PCR, use of restriction enzymes and Southern blot analysis. Subsequently, I investigated the DNA state of neoplasic cervix cells infected by HPV and collaborated in the detection of HPV (supported by the PAHO and the IARC). I received training in cell culture, PCR techniques and use of restriction enzymes. Later, I examined the mechanism of lysosomal protein secretion by epididymal epithelial cells (in vitro and in vivo). Moreover, I studied the mannose-6-phosphate receptor and its ligands during the perinatal development of several organs of the rat. I acquired expertise in cell culture, RT-PCR, confocal-immunomicroscopy, pulse chase analysis, immunohystochemistry, light and electronic microscopy, co-immunoprecipitation and immunoblotting. Currently, I am studying the molecular mechanisms of several epididymal lysosomal proteins on sperm maturation, capacitation and fertilization. *Information provided by the agent in SIGEVA

Lines of Investigation

Biología celular del epidídimo y su relación con la maduración espermática CIENCIAS NATURALES Y EXACTAS - Ciencias Biológicas - Biología Reproductiva (aspectos médicos van en 3 "Ciencias Médicas y de la Hídrico Salud")

Technological Capacities

  • 6. Ciencias biológicas
    • 2. Biología / Biotecnología
      • 2.1. Bioquímica / biofísica
      • 2.2. Biología celular y molecular
      • 2.4. Ensayos in vitro, experimentos

Key Words

maduración espermáticaepidídimolysosomal enzymesepididymisenzimas lisosomalessperm maturation

Education

2004 - 2010

Doctora en Ciencias Biológicas

UNIVERSIDAD NACIONAL DE CUYO

1996 - 2003

Licenciada en Biología Molecular

UNIVERSIDAD NACIONAL DE SAN LUIS


S&T HR Training

Co-director of

Science and Technology Production

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