RONDAL SIMBAÑA, JONATHAN DARIO

Internal doctoral strategic topics

SPECIALITY:

Obtención y caracterización de gelatina de pescado

Scientific discipline:

Food engineering and Biotechnology

Topic:

CHARACTERIZATION AND TECHNOLOGICAL PROSPECTIVE OF GELATIN OBTAINED FROM WASTE FROM FISH PROCESSING

Workplace

GRUPO DE INV. PRESERVACION Y CALIDAD DE ALIMENTOS (GIPCAL, UNMDP) Depends on

UNIVERSIDAD NACIONAL DE MAR DEL PLATA (UNMDP)

FACULTAD DE INGENIERIA

DEPARTAMENTO DE INGENIERIA QUIMICA Y EN ALIMENTOS

	Address:
	AV.JUAN B.JUSTO 4302, 7600 - Mar del Plata - Buenos Aires - Argentina

Contact:

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S&T Expertise*

Drosophila melanogaster hemolymph cells are confirmed as a model to study the activation of immune system due to foreign stimuli like iron nanoparticles. The toxicity of nanoparticles is a cause for concern due to their effect on human health and the environment. The aim of this study was to detect the activation of cellular immune response in Drosophila larvae through the observation of hemolymph composition, DNA damage and larval viability, after the exposure to 500 ppm and 1000 ppm chitosan-coated magnetite nanoparticles for 24 hours. Our results showed activation of cellular immune response after exposure to the nanoparticles owing to the increment of hemocytes, the emergence of lamellocytes and the presence of apoptotic hemocytes. In addition, chitosan-coated magnetite nanoparticles produce DNA damage detected by comet assay as well as low viability of larvae. No DNA damage is showed at 500 ppm. The cellular toxicity is directly associated with 1000 ppm. *Information provided by the agent in SIGEVA

Lines of Investigation

Genotoxicidad Natural and exact sciences - Biological sciences - Biodiversity conservation

Technological Capacities

6. Biological sciences

2. Biology/Biotechnology

2.2. Cellular and Molecular Biology
2.6. Molecular design
2.10. Synthetic Biology
2.3. Genetic Engineering
2.7. Toxicology
2.11. Protein Engineering
2.1. Biochemistry/Biophysics
2.5. Microbiology
2.4. In vitro Testing, Trials
2.9. Enzyme Technology
2.8. Bionics

3. Genome Research

3.3. Population genetics
3.2. Gene Expression, Proteom Research
3.1. Bioinformatics

6. Industrial Biotechnology

6.3. Biobased high-performance materials
6.7. Bioplastics
6.4. Biobased Materials
6.8. Biopolymers
6.2. Biobased chemical building blocks
6.6. Biolubricants
6.1. Bio- Composites
6.5. Biological Nanomaterials
6.9. Bioprocesses

4. Micro- and Nanotechnology related to Biological sciences

Key Words

Hemolymphapoptosischitosan magnetite nanoparticles

Education

2022 - 2023

Máster en Ciencias Ambientales Evaluación del Impacto Ambiental

UNIVERSIDAD YACAMBÚ

2021 - 2022

Máster en Bioética

UNIVERSITAT INTERNACIONAL VALENCIANA

2020 - 2021

Especialista en Gestión de Proyectos de Desarrollo

AREA DE ESTADO Y POLITICAS PUBLICAS, FACULTAD LATINOAMERICANA DE CIENCIAS SOCIALES

2009 - 2016

Ingeniero en Biotecnología

DEPARTAMENTO DE CIENCIAS DE LA VIDA Y LA AGRICULTURA, UNIVERSIDAD DE LAS FUERZAS ARMADAS

Directed by

CZERNER, MARINA

Scientific Research Career at CONICET

CZERNER, Marina Scientific Research Career at CONICET

Co-directed by

AGUSTINELLI, SILVINA PAOLA

Scientific Research Career at CONICET

AGUSTINELLI, Silvina Paola Scientific Research Career at CONICET

Science and Technology Production

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