Science and Technology Production

Sensitivity analysis for the EEG forward problem

Article

Authorship:

Maria Inés Troparevsky ; Diana Rubio ; SAINTIER, NICOLAS BERNARD CLAUDE

Date:

2010

Publishing House and Editing Place:

Frontiers Editorial Office

Magazine:

Frontiers in computational neuroscience, vol. 4 (pp. 1-6) - ISSN 1662-5188
Frontiers Editorial Office

ISSN:

1662-5188

Summary *

Sensitivity Analysis can provide  useful information when one is interested in identifying the parameter $\theta$ of a system since it measures the variations of the output $u$ when $\theta$ changes. In the literature two different sensitivity functions are frequently used: the Traditional Sensitivity Functions (TSF) defined as $\frac{\partial u}{\partial \theta}$ and the Generalized Sensitivity Functions (GSF) that help to determine  the time instants where the output of a dynamical system has more information about the value of its parameters in order to carry on an estimation process. Both functions were considered  by some  authors who  compared their results for different dynamical systems (see \textit{Banks 2008, Banks 2001, Kappel 2006}).  %\cite{banks1},  In this work we apply the TSF and the GSF to analyze the sensitivity of the 3D Poisson-type equation with interfaces of the Forward Problem of Electroencephalography (EEG).   In a simple model where we consider the head as a volume consisting of nested homogeneous sets, we  establish the differential equations that correspond to TSF with respect to  the value of the conductivity of the different tissues   and deduce the corresponding Integral Equations. Afterwards we compute the GSF for the same model.  We perform some numerical experiments for  both types of sensitivity functions    %on a simple head model  and compare the results.  Information provided by the agent in SIGEVA

Key Words

forward problem of electroencephalographygeneralized sensitivitytraditional sensitivity