Science and Technology Production
Article
Authorship
Date
2006
Publishing House and Editing Place
Thieme Stuttgart
Magazine
SYNTHESIS-STUTTGART,
vol. -
(pp. 187-220)
Thieme Stuttgart
Summary
Information provided by the agent in
SIGEVA
Compounds bearing the isochroman ring system are found in natural and synthetic products of interest. The oxa-Pictet-Spengler condensation is a valuable tool for the preparation of polysubstituted isochromans and related oxygen-bearing heterocycles. The different staging of the oxa-Pictet-Spengler reaction, as well as the scope and limitations of this transformation, are discussed.
Key Words
isochromansMacrolactam cyclizationoxa-Pictet–SpenglerChemical SynthesisNatural products