Science and Technology Production
Congress
Authorship
Anzardi Ruffino, Lara
;
Quiroz, Sol
;
Suarez, Joaquin
;
Mary, Verónica
;
Yañez Santos, Anahí
;
Theumer, Martín
;
Lascano, Hernán Ramiro
;
Lescano López, Ignacio
Date
2025
Publishing House and Editing Place
SAIB
Summary
Information provided by the agent in
SIGEVA
Autophagy is a conserved eukaryotic process that maintains cellular homeostasis and regulates stress responses and development through selective degradation and recycling of cellular components. In plants, autophagy also contributes to immunity, balancing growth and defense. Cargo receptors such as NBR1 (Neighbour of Breast cancer 1) confer selectivity by recognizing specific substrates and delivering them to the autophagic machinery. Elevated temperatures promote thermomorphogenesis, reshaping...
Autophagy is a conserved eukaryotic process that maintains cellular homeostasis and regulates stress responses and development through selective degradation and recycling of cellular components. In plants, autophagy also contributes to immunity, balancing growth and defense. Cargo receptors such as NBR1 (Neighbour of Breast cancer 1) confer selectivity by recognizing specific substrates and delivering them to the autophagic machinery. Elevated temperatures promote thermomorphogenesis, reshaping development by altering hormone signaling and increasing susceptibility to pathogens. In particular, the accumulation of abscisic acid (ABA) has been associated with enhanced pathogen susceptibility. We previously showed that infection by Pseudomonas syringae enhances autophagic flux and NBR1 turnover in Arabidopsis thaliana under high temperatures. Interestingly, nbr1-2 mutants grown at 29 °C were more susceptible to P. syringae pv. maculicola (Psm). Here, we investigated the role of NBR1 in hormonal, developmental, and defense responses under elevated temperature. Physiological and developmental traits associated with high temperature, including hormone levels, expression of hormone-related genes, petiole elongation, and photosynthetic pigments content, were analyzed in wild-type and nbr1-2 plants infected with Psm and grown at 22 °C or 29 °C. Loss of NBR1 led to increased accumulation of chlorophylls and carotenoids, and marked changes in hormone-related gene expression at 29 °C. Notably, ABA biosynthesis and signaling were enhanced in nbr1-2 mutants. Consistently, ABI5 protein accumulated in nbr1-2 and physically interacted with NBR1, suggesting that NBR1 directs ABI5 turnover through autophagy. The associated developmental and pigment changes further support a role for NBR1 in modulating growth and stress responses during thermomorphogenesis. These findings identify NBR1 as a novel regulator of ABA signaling and plant defense under elevated temperatures, linking selective autophagy to hormonal crosstalk in stress adaptation.
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Key Words
WARMINGPLANT IMMUNITYAUTOPHAGYABSCISIC ACID