Science and Technology Production
Article
Authorship
Biswal, Suryanarayan
;
BORGONOVO, JANINA EDITH
;
Freites, Carlos L.
;
Martínez-Cerdeño, Verónica
;
Mishra, Rajnikant
;
Maurya, Shashank K.
;
Muñoz, Estela M.
Date
2025
Publishing House and Editing Place
Frontiers Media S.A.
Magazine
Frontiers in Immunology,
vol. 16
Frontiers Media S.A.
Summary
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SIGEVA
The intricate interplay between the central nervous system (CNS) and the immune system is increasingly recognized as fundamental to both neurological health and disease. This second volume of the Community Series in Trends in Neuroimmunology continues to spotlight emerging insights into how brain-resident and peripheral immune cells communicate across anatomical and functional borders, shaping responses in both homeostatic and pathological contexts. Ten peer-reviewed manuscripts, including seve...
The intricate interplay between the central nervous system (CNS) and the immune system is increasingly recognized as fundamental to both neurological health and disease. This second volume of the Community Series in Trends in Neuroimmunology continues to spotlight emerging insights into how brain-resident and peripheral immune cells communicate across anatomical and functional borders, shaping responses in both homeostatic and pathological contexts. Ten peer-reviewed manuscripts, including seven original articles, two reviews, and one opinion, encompass this special volume. Ninety-five authors from research laboratories located in twelve countries: Brazil, Canada, Chile, Denmark, France, Germany, Italy, United Arab Emirates, United Kingdom, United States, Republic of Korea, and Singapore, took part in this initiative. These diverse arrays of articles underscore the intricate and evolving dialogue between the central nervous and immune systems, both at the brain borders and within the parenchyma. The contributions offer cutting-edge insights into how peripheral and brain-resident immune cells influence neurological health, disease progression, and therapeutic responsiveness across conditions like MS, PD, SPS, and age-related cognitive decline. By bridging experimental and clinical perspectives, these studies challenge long-held paradigms of CNS immune privilege and lay critical groundwork for future immunomodulatory strategies in neurodegenerative and neuroinflammatory diseases.
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Key Words
NEURODEGENERATIONMICROGLIAPERIPHERAL IMMUNE CELLSNEUROINFLAMMATION