Functional analysis of MAPT mutations associated with human taupathies: development of new experimental models and optimization of therapeutic strategies
GODOY CRUZ 2390, C1425FQD - Capital Federal - Argentina
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My main research interest is understanding how dysregulation of the microtubule network can lead to neurological disease. For my graduate training at Vanderbilt University, I have decided to complement my undergraduate studies on model organisms with protein-centered, microscopy-oriented research, under Dr. Marija Zanic. Our laboratory focuses on studying how a myriad of microtubule-associated proteins modulate microtubule dynamics and organization, using multidisciplinary in vitro reconstituti...My main research interest is understanding how dysregulation of the microtubule network can lead to neurological disease. For my graduate training at Vanderbilt University, I have decided to complement my undergraduate studies on model organisms with protein-centered, microscopy-oriented research, under Dr. Marija Zanic. Our laboratory focuses on studying how a myriad of microtubule-associated proteins modulate microtubule dynamics and organization, using multidisciplinary in vitro reconstitution approaches. This research environment will not only help me develop mastery of cutting-edge experimental techniques in molecular and cell biology, protein biochemistry, biophysics and bioengineering, but it will also facilitate my training in literature discussion, scientific writing, oral presentations, and critical thinking.
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Lines of Investigation
Proteínas asociadas a microtúbulos
Natural and exact sciences
Biological sciences
Biochemistry and molecular biology (same as 3.1.10)
Citoesqueleto neuronal
Natural and exact sciences
Biological sciences
Cell biology, microbiology
Neurobiología celular, taupatías
Medical and health sciences
Basic medicine
Neurosciences (includes psychophysiology)
Technological Capacities
6 - Biological sciences
6.1 - Medicine, Human Health
6.1.12 - Neurology, Brain Research
6.2 - Biology/Biotechnology
6.2.1 - Biochemistry/Biophysics
6.2.2 - Cellular and Molecular Biology
6.2.4 - In vitro Testing, Trials
6.2.6 - Molecular design
6.2.11 - Protein Engineering
Key Words
Citoesqueleto neuronalTaupatíasMicrotubule-associated proteinsProteínas asociadas a microtúbulosNeuronal cytoskeletonTaupathies