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MATTERA, VANESA SOLEDAD

Postdoctoral (internal)

Speciality
Neurociencias
Scientific discipline
Biology - Medical Sciences
Topic
The role of extracellular vesicles on the oligodendroglial cell during demyelination/remyelination
Workplace
INSTITUTO DE QUIMICA Y FISICOQUIMICA BIOLOGICAS "PROF. ALEJANDRO C. PALADINI" (IQUIFIB, CONICET-UBA)
Dependencies
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Address:
JUNIN 956, 1113 - Capital Federal - Argentina
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Summary Information provided by the agent in SIGEVA
Animal models: Handling and maintenance of murine models (cuprizone-induced demyelination, transgenic lines), animal genotyping, perfusion, and cryostat sectioning of adult, neonatal, and embryonic brain and spinal cord.Molecular biology: PCR, qRT-PCR, Western blot, Gateway cloning, RNAscope.Microscopy: Confocal and fluorescence microscopy, TEM, SEM, time-lapse imaging, ImageJ/FIJI analysis.Cell analysis: Primary cultures (immunopanning, McCarthy & de Vellis), cell lines, organotypic slice cult... Animal models: Handling and maintenance of murine models (cuprizone-induced demyelination, transgenic lines), animal genotyping, perfusion, and cryostat sectioning of adult, neonatal, and embryonic brain and spinal cord.Molecular biology: PCR, qRT-PCR, Western blot, Gateway cloning, RNAscope.Microscopy: Confocal and fluorescence microscopy, TEM, SEM, time-lapse imaging, ImageJ/FIJI analysis.Cell analysis: Primary cultures (immunopanning, McCarthy & de Vellis), cell lines, organotypic slice cultures, immunocytochemistry.Myelination: Histological analysis, myelin staining, quantitative assessment including TEM.Data analysis: Gene expression analysis; R for statistics and visualization.Other techniques: Extracellular vesicle isolation and characterization (SEC, DLS, NTA); intranasal and intracranial drug/nanoparticle delivery.
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Lines of Investigation

Neurobiologia

Natural and exact sciences

  • Biological sciences
  • Cell biology, microbiology

Glicobiología

Natural and exact sciences

  • Biological sciences
  • Biochemistry and molecular biology (same as 3.1.10)

Vesiculas extracelulares como nanovehiculos

Engineering and technologies

  • Nanotechnology
  • Nano-procesamiento (aplicaciones en nanoescala, los biomateriales van en 2.9 "Biotecnología Industrial")

Glicobiología

Natural and exact sciences

  • Biological sciences
  • Biochemistry and molecular biology (same as 3.1.10)

Neurobiologia

Natural and exact sciences

  • Biological sciences
  • Cell biology, microbiology

Vesiculas extracelulares como nanovehiculos

Engineering and technologies

  • Nanotechnology
  • Nano-procesamiento (aplicaciones en nanoescala, los biomateriales van en 2.9 "Biotecnología Industrial")
Technological Capacities

6 - Biological sciences

6.2 - Biology/Biotechnology

  • 6.2.1 - Biochemistry/Biophysics
  • 6.2.2 - Cellular and Molecular Biology
  • 6.2.3 - Genetic Engineering
  • 6.2.4 - In vitro Testing, Trials
  • 6.2.5 - Microbiology
  • 6.2.9 - Enzyme Technology
  • 6.2.11 - Protein Engineering

6.3 - Genome Research

  • 6.3.1 - Bioinformatics
  • 6.3.2 - Gene Expression, Proteom Research
Key Words
Biología molecularBioquímica estructuralGlicobiologíaMolecular biologyStructural biochemistryGlycobiologyGenética de levadurasYeast geneticsNeurobiologiaMielinizacionRemielinizacionEnfermedades desmielinizantesAdministracion intranasal de drogasVesiculas extracelularesNanoentregaNeurobiologyMyelinationRemyelinationDemyelinating diseasesIntranasal administrationExtracellular vesiclesNanodelivery
Education

2017 - 2023

Doctorado de la Universidad de Buenos Aires - Área Farmacia y Bioquímica

FACULTAD DE FARMACIA Y BIOQUIMICA, UNIVERSIDAD DE BUENOS AIRES

2008 - 2016

Licenciada en Biotecnología

UNIVERSIDAD NACIONAL DE QUILMES

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