Medical Sciences - Biochemistry and Molecular Biology
Topic
Recovery of voluntary locomotor activity after a chronic spinal cord injury. Netrin-1 as a therapeutical approach.
Workplace
LABORATORIO DE MEDICINA EXPERIMENTAL
Dependencies
HOSPITAL ALEMAN
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Address:
AV. PUEYRREDON 1640 - Capital Federal - Argentina
SummaryInformation provided by the agent in SIGEVA
The goal of my project is to investigate the mechanism by Galectin-1 in its dimeric form promotes axonal regeneration in spinal cord injury. We plan to measure changes in hydrogen peroxide production in damage axons with different levels of dying back axons. I have the expertise, necessary to successfully carry out the proposed work. I have a broad background in Techniques such as: Spinal cord injury, live cell video imaging, time lapse imaging, 4D microscopy, FRET and FRAP techniques. Two phot...The goal of my project is to investigate the mechanism by Galectin-1 in its dimeric form promotes axonal regeneration in spinal cord injury. We plan to measure changes in hydrogen peroxide production in damage axons with different levels of dying back axons. I have the expertise, necessary to successfully carry out the proposed work. I have a broad background in Techniques such as: Spinal cord injury, live cell video imaging, time lapse imaging, 4D microscopy, FRET and FRAP techniques. Two photons Microscopy. Atomic Force Microscopy.Organotypic spinal cord culture. Stereotaxic surgery. Clearing technique with 1-photon microscopy expertise (developed by our Group, Quintá et.al. 2015) and expertise in the novel Brainbow techinque. I received a special training in Bio-sensor microscopy in an internship in the laboratory of Dr. Christian González Billault, Institute for Cell Dynamics and Biotechnology (ICDB) Faculty of Sciences, Universidad de Chile.
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Lines of Investigation
Neuro regeneracion
Medical and health sciences
Basic medicine
Neurosciences (includes psychophysiology)
Technological Capacities
6 - Biological sciences
6.1 - Medicine, Human Health
6.1.10 - Medical Research
6.1.12 - Neurology, Brain Research
6.1.15 - Surgery
6.2 - Biology/Biotechnology
6.2.1 - Biochemistry/Biophysics
6.2.2 - Cellular and Molecular Biology
6.2.4 - In vitro Testing, Trials
6.2.6 - Molecular design
Key Words
Lesiones de médula espinalRegeneración NeuronalmicroscopyAxonal regenerationMicroscopia spinal cord injury
Education
2008-2011
Doctor de la Universidad de Buenos Aires, área Neurociencias
UNIVERSIDAD DE BUENOS AIRES
2001-2007
Bioquímico
UNIVERSIDAD DE BUENOS AIRES
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